SrasV1, Main, Exploration, bibRecord, 005418

Clinicopathology of severe acute respiratory syndrome: an autopsy case report.

Identifieur interne : 005418 ( Main/Exploration ); précédent : 005417; suivant : 005419

Clinicopathology of severe acute respiratory syndrome: an autopsy case report.

Auteurs : Cheng-Hsiang Hsiao [Taïwan] ; Mu-Zong Wu ; Swen-Wan Hsieh ; Lin-Chen Chien ; Kung-Chang Hwang ; Ih-Jen Su

Source :

Journal of the Formosan Medical Association = Taiwan yi zhi [ 0929-6646 ] ; 2004.

RBID : pubmed:15490031

Descripteurs français

KwdFr :
- Adulte, Autopsie, Bronchopneumonie (anatomopathologie), Coronavirus (isolement et purification), Femelle, Foie (anatomopathologie), Humains, Muqueuse nasale (virologie), Noeuds lymphatiques (anatomopathologie), Poumon (anatomopathologie), Rate (anatomopathologie), Syndrome respiratoire aigu sévère (anatomopathologie).
MESH :
- anatomopathologie : Bronchopneumonie, Foie, Noeuds lymphatiques, Poumon, Rate, Syndrome respiratoire aigu sévère.
- isolement et purification : Coronavirus.
- virologie : Muqueuse nasale.
- Adulte, Autopsie, Femelle, Humains.

English descriptors

KwdEn :
- Adult, Autopsy, Bronchopneumonia (pathology), Coronavirus (isolation & purification), Female, Humans, Liver (pathology), Lung (pathology), Lymph Nodes (pathology), Nasal Mucosa (virology), Severe Acute Respiratory Syndrome (pathology), Spleen (pathology).
MESH :
- isolation & purification : Coronavirus.
- pathology : Bronchopneumonia, Liver, Lung, Lymph Nodes, Severe Acute Respiratory Syndrome, Spleen.
- virology : Nasal Mucosa.
- Adult, Autopsy, Female, Humans.

Abstract

In mid-April 2003, a major outbreak of severe acute respiratory syndrome (SARS) developed in Taiwan. During the outbreak, SARS-associated coronavirus (SARS-CoV) was documented in 346 patients and 73 of them died. Autopsy was performed in 9 of the suspected SARS patients who died during the outbreak, but SARS was the cause of death in only 1 of these patients. Here we report the histological features of this patient and their clinicopathological correlations. The patient, a 36-year-old Indonesian woman, was a caretaker working for a Taiwanese family. She stayed in Taipei Jen-Chi Hospital from April 10 to April 19 to take care of her elderly employer. She developed fever on April 21 and respiratory distress on April 25, and received ribavirin, intravenous immunoglobulin, and steroid. The respiratory distress persisted and worsened, and intubation was performed on April 27. The respiratory condition improved initially after mechanical ventilation, but subcutaneous emphysema and pneumomediastinum developed on May 1. Her condition deteriorated rapidly and she died on May 2, 11 days after the onset of fever. Autopsy was performed on the same day. Histologically, the lungs showed severe diffuse alveolar damage and bronchopneumonia, but no viral inclusion. The spleen and lymph nodes revealed lymphoid depletion and the liver showed microvesicular steatosis. No specific pathological change was seen in the gastrointestinal tract and kidneys. SARS-CoV genome was detected in the nasopharyngeal aspirate and the autopsy lung specimen.

PubMed: 15490031

Affiliations:

Taïwan

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinicopathology of severe acute respiratory syndrome: an autopsy case report.</title>
<author><name sortKey="Hsiao, Cheng Hsiang" sort="Hsiao, Cheng Hsiang" uniqKey="Hsiao C" first="Cheng-Hsiang" last="Hsiao">Cheng-Hsiang Hsiao</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, National Taiwan University Hospital, Taipei 100, Taiwan.</nlm:affiliation>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea>Department of Pathology, National Taiwan University Hospital, Taipei 100</wicri:regionArea>
<wicri:noRegion>Taipei 100</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wu, Mu Zong" sort="Wu, Mu Zong" uniqKey="Wu M" first="Mu-Zong" last="Wu">Mu-Zong Wu</name>
</author>
<author><name sortKey="Hsieh, Swen Wan" sort="Hsieh, Swen Wan" uniqKey="Hsieh S" first="Swen-Wan" last="Hsieh">Swen-Wan Hsieh</name>
</author>
<author><name sortKey="Chien, Lin Chen" sort="Chien, Lin Chen" uniqKey="Chien L" first="Lin-Chen" last="Chien">Lin-Chen Chien</name>
</author>
<author><name sortKey="Hwang, Kung Chang" sort="Hwang, Kung Chang" uniqKey="Hwang K" first="Kung-Chang" last="Hwang">Kung-Chang Hwang</name>
</author>
<author><name sortKey="Su, Ih Jen" sort="Su, Ih Jen" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2004">2004</date>
<idno type="RBID">pubmed:15490031</idno>
<idno type="pmid">15490031</idno>
<idno type="wicri:Area/PubMed/Corpus">002B08</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002B08</idno>
<idno type="wicri:Area/PubMed/Curation">002B08</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002B08</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002D83</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002D83</idno>
<idno type="wicri:Area/Ncbi/Merge">000B26</idno>
<idno type="wicri:Area/Ncbi/Curation">000B26</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000B26</idno>
<idno type="wicri:doubleKey">0929-6646:2004:Hsiao C:clinicopathology:of:severe</idno>
<idno type="wicri:Area/Main/Merge">005853</idno>
<idno type="wicri:Area/Main/Curation">005418</idno>
<idno type="wicri:Area/Main/Exploration">005418</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Clinicopathology of severe acute respiratory syndrome: an autopsy case report.</title>
<author><name sortKey="Hsiao, Cheng Hsiang" sort="Hsiao, Cheng Hsiang" uniqKey="Hsiao C" first="Cheng-Hsiang" last="Hsiao">Cheng-Hsiang Hsiao</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, National Taiwan University Hospital, Taipei 100, Taiwan.</nlm:affiliation>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea>Department of Pathology, National Taiwan University Hospital, Taipei 100</wicri:regionArea>
<wicri:noRegion>Taipei 100</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wu, Mu Zong" sort="Wu, Mu Zong" uniqKey="Wu M" first="Mu-Zong" last="Wu">Mu-Zong Wu</name>
</author>
<author><name sortKey="Hsieh, Swen Wan" sort="Hsieh, Swen Wan" uniqKey="Hsieh S" first="Swen-Wan" last="Hsieh">Swen-Wan Hsieh</name>
</author>
<author><name sortKey="Chien, Lin Chen" sort="Chien, Lin Chen" uniqKey="Chien L" first="Lin-Chen" last="Chien">Lin-Chen Chien</name>
</author>
<author><name sortKey="Hwang, Kung Chang" sort="Hwang, Kung Chang" uniqKey="Hwang K" first="Kung-Chang" last="Hwang">Kung-Chang Hwang</name>
</author>
<author><name sortKey="Su, Ih Jen" sort="Su, Ih Jen" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name>
</author>
</analytic>
<series><title level="j">Journal of the Formosan Medical Association = Taiwan yi zhi</title>
<idno type="ISSN">0929-6646</idno>
<imprint><date when="2004" type="published">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Autopsy</term>
<term>Bronchopneumonia (pathology)</term>
<term>Coronavirus (isolation & purification)</term>
<term>Female</term>
<term>Humans</term>
<term>Liver (pathology)</term>
<term>Lung (pathology)</term>
<term>Lymph Nodes (pathology)</term>
<term>Nasal Mucosa (virology)</term>
<term>Severe Acute Respiratory Syndrome (pathology)</term>
<term>Spleen (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Autopsie</term>
<term>Bronchopneumonie (anatomopathologie)</term>
<term>Coronavirus (isolement et purification)</term>
<term>Femelle</term>
<term>Foie (anatomopathologie)</term>
<term>Humains</term>
<term>Muqueuse nasale (virologie)</term>
<term>Noeuds lymphatiques (anatomopathologie)</term>
<term>Poumon (anatomopathologie)</term>
<term>Rate (anatomopathologie)</term>
<term>Syndrome respiratoire aigu sévère (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Bronchopneumonie</term>
<term>Foie</term>
<term>Noeuds lymphatiques</term>
<term>Poumon</term>
<term>Rate</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Bronchopneumonia</term>
<term>Liver</term>
<term>Lung</term>
<term>Lymph Nodes</term>
<term>Severe Acute Respiratory Syndrome</term>
<term>Spleen</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Muqueuse nasale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Nasal Mucosa</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Autopsy</term>
<term>Female</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Autopsie</term>
<term>Femelle</term>
<term>Humains</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In mid-April 2003, a major outbreak of severe acute respiratory syndrome (SARS) developed in Taiwan. During the outbreak, SARS-associated coronavirus (SARS-CoV) was documented in 346 patients and 73 of them died. Autopsy was performed in 9 of the suspected SARS patients who died during the outbreak, but SARS was the cause of death in only 1 of these patients. Here we report the histological features of this patient and their clinicopathological correlations. The patient, a 36-year-old Indonesian woman, was a caretaker working for a Taiwanese family. She stayed in Taipei Jen-Chi Hospital from April 10 to April 19 to take care of her elderly employer. She developed fever on April 21 and respiratory distress on April 25, and received ribavirin, intravenous immunoglobulin, and steroid. The respiratory distress persisted and worsened, and intubation was performed on April 27. The respiratory condition improved initially after mechanical ventilation, but subcutaneous emphysema and pneumomediastinum developed on May 1. Her condition deteriorated rapidly and she died on May 2, 11 days after the onset of fever. Autopsy was performed on the same day. Histologically, the lungs showed severe diffuse alveolar damage and bronchopneumonia, but no viral inclusion. The spleen and lymph nodes revealed lymphoid depletion and the liver showed microvesicular steatosis. No specific pathological change was seen in the gastrointestinal tract and kidneys. SARS-CoV genome was detected in the nasopharyngeal aspirate and the autopsy lung specimen.</div>
</front>
</TEI>
<affiliations><list><country><li>Taïwan</li>
</country>
</list>
<tree><noCountry><name sortKey="Chien, Lin Chen" sort="Chien, Lin Chen" uniqKey="Chien L" first="Lin-Chen" last="Chien">Lin-Chen Chien</name>
<name sortKey="Hsieh, Swen Wan" sort="Hsieh, Swen Wan" uniqKey="Hsieh S" first="Swen-Wan" last="Hsieh">Swen-Wan Hsieh</name>
<name sortKey="Hwang, Kung Chang" sort="Hwang, Kung Chang" uniqKey="Hwang K" first="Kung-Chang" last="Hwang">Kung-Chang Hwang</name>
<name sortKey="Su, Ih Jen" sort="Su, Ih Jen" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name>
<name sortKey="Wu, Mu Zong" sort="Wu, Mu Zong" uniqKey="Wu M" first="Mu-Zong" last="Wu">Mu-Zong Wu</name>
</noCountry>
<country name="Taïwan"><noRegion><name sortKey="Hsiao, Cheng Hsiang" sort="Hsiao, Cheng Hsiang" uniqKey="Hsiao C" first="Cheng-Hsiang" last="Hsiao">Cheng-Hsiang Hsiao</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005418 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005418 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:15490031
   |texte=   Clinicopathology of severe acute respiratory syndrome: an autopsy case report.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:15490031" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

Serveur d'exploration SRAS

Clinicopathology of severe acute respiratory syndrome: an autopsy case report.

Clinicopathology of severe acute respiratory syndrome: an autopsy case report.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.